^{Health care medicine HLD Series Hopper Mixing Machine(hopper mixer) for pharmaceutical industry(Hopper mixer ) (Hopper blender )( IBC BIN BLENDER, Hopper mixing machine )}

Introduction

Manufacture of solid dosage forms implies mix of the active ingredient with excipients, in order to have content uniformity so that, during the subsequent dosage (compression, filling of capsules and pouches, etc...) the dose units with the proper contents are obtained.

The conventional mixing systems use fixed rotation mixers that must be discharged to containers where they are stored until the feeding moment. Instead, the intermediate bulk container (IBC) technology is composed by a fixed blending station, with container units or mobile bins.

Therefore, after filling a container unit with the product, it will be used for three functions:

a) Blending

b) Storage

c) Feeding

Bin Blenders are an integral module in the solid material handling process. They are known for their ability to achieve high blend uniformity in a short period of time. The Bin Blender is designed to receive, lock, lift and blend an IBC.

The same container that is used throughout the entire manufacturing process also serves as the blending unit. One of the inherent advantages of using an Intermediate Bulk Container (IBC) is that it permits the homogeneous blending of multiple ingredients without the need to transfer the material to and from another machine. This eliminates cross contamination, costly product change-over times and blender cleaning and preparation. Our line of Bin Blenders permits the easy loading of the IBC without a forklift. After blending, the IBC can be lifted and positioned above a process for discharging via the use of one of our post lifts.

This equipment is mainly composed of frame, rotate cage; drive system, lifting system, braking system and control system.

Before start of blending process, operator loads the bin into the rotate cage, then presses “Confirm” key on touch panel, the bin will be automatically raised to set position and clamped.

On receipt of bin-clamped signal by sensor, the drive system starts blending as programmed according to setting of time and speed.

On finish of blending process, brake system works automatically, to stop the rotate cage until it comes to a horizontal position.

Then, the lifting system works to land the bin to the ground and on reaching that position, the whole system stops automatically.

Finally, process data of the batch is printed out. Operator moves out the bin from the rotate cage and transfers it to next process.

The ability to obtain a homogeneous blend of multiple ingredients in an IBC without mechanical intrusion.

The transfer of product to and from another machine is eliminated.

Containment and ergonomic situations are greatly improved.

The clamping arm is simple, hygienic, and safe.

Safety interlock available

Soft start and stop

Optimized blending effect

Variable blending speed

Remote operator panel, operator interface terminal with recipe controlled blending

PLC controls

Manual/ Maintenance override controls

Carbon steel or stainless steel construction, cladding of all open framework with stainless steel sheets

It is designed according to GMP guidelines.

Preface

Through years of studying, comparing and absorbing both domestic and foreign machines, we develop our own design of HLD series hopper mixing machine.

The main structure feature of the mixer is: the mixing body (material vessel) and the rotating axis form a angle of 30°. When the material is rotating, the material also makes tangent movement along the wall of the vessel. The function of these to movements makes all points of material moves in complicated ways, changes their positions all the time, so to have very high mixing efficiency.

Principle

Through years of studying, comparing and absorbing both domestic and foreign machines, we develop our own design of HLD series hopper mixing machine.

The main structure feature of the mixer is: the mixing body (material vessel) and the rotating axis form a angle of 30°. When the material is rotating, the material also makes tangent movement along the wall of the vessel. The function of these to movements makes all points of material moves in complicated ways, changes their positions all the time, so to have very high mixing efficiency.

Feature

1. The structure is reasonable, adopting double hoisting devices, motor rotation, flexible coupler. The performance is stable, the upkeep and maintenance and simpler, and there's no problem of leakage.

2. Adopt programmed control system, technical parameters setting system, machine stops system for safety, automatic accurate positioning system, operation, and automatic record printing system, that fully meet processing equipment of pharmaceutical companies. Fully automatic production is realized, and the operation is very simple.

3. To ensure the quality of the machine, we adopt outsourcing parts with high quality for this machine.

4. Equipped with fine manufactured hopper that fully meet the requirements of GMP, no residues of discharge, and it's easy for cleaning or washing.

5. We supply series product for material conveying. It forms advanced process together with the hopper mixing machine.

Remarks: If customer has any special requirements, please customize.

lso makes tangent movement along the wall of the vessel. The function of these to movements makes all points of material moves in complicated ways, changes their positions all the time, so to have very high mixing efficiency.

1. Through years of studying, comparing and absorbing both domestic and foreign machines, we develop our own design of HLD series hopper mixing machine.
2. The main structure feature of the mixer is: the mixing body (material vessel) and the rotating axis form a angle of 30°. When the material is rotating, the material also makes tangent movement along the wall of the vessel. The function of these to movements makes all points of material moves in complicated ways, changes their positions all the time, so to have very high mixing efficiency.
3. Through years of studying, comparing and absorbing both domestic and foreign machines, we develop our own design of HLD series hopper mixing machine.
4. The main structure feature of the mixer is: the mixing body (material vessel) and the rotating axis form a angle of 30°. When the material is rotating, the material also makes tangent movement along the wall of the vessel. The function of these to movements makes all points of material moves in complicated ways, changes their positions all the time, so to have very high mixing efficiency.

Changzhou Yibu Drying Equipment Co., Ltd. is a leading manufacturer of drying, mixing, and granulating equipment in China, a specially-designated enterprise of China Association for Pharmaceutical Equipment (CAPE) and China General Machinery Industry Association (CGMA) Drying Equipment Branch. The factory covers an area of over 50,000 m2, has fixed assets of CNY 35 million, with more than 180 sets of special processing equipment and strong technical force. The company owns the provincial famous trademark of "YIBU", and has passed the ISO9001 & ISO14001 certifications.
The founder, Mr Zha Guocai has devoted more than 30 years in R&D, production and business of drying equipment. He holds the post of Deputy Director-General of China General Machinery Industry Association (CGMA) Drying Equipment Branch for a long time. The company pays great attention to science and technology innovation, has collaborated with Medicine Design Institutes in Shanghai, Wuhan, Chongqing and other places, Shenyang Chemical Research Institute, Qinghua University, Shanghai Jiaotong University, Dalian University of Technology, etc. The company launched 3-5 new products to the market every year. In 1998, YIBU established "China Research Center of Drying and Granulating" with the approval of relevant state department, and cooperated with pharmaceutical, chemical and food industries to research and develop new technologies related to drying, granulating and mixing, etc. The factory also has a variety of test prototypes in the laboratory for customers' trials.
The company sold equipment to USA, Mexico, Columbia, Guatemala, Brazil, Peru, Australia, New Zealand, Ghana, Russia, Cyprus, Greece, Iran, Indonesia, Philippines, Korea, Japan, Taiwan, Hong Kong and other countries.